戚建平

发布者:张毅发布时间:2024-08-13浏览次数:13

姓名:戚建平

职称:教授

电子邮件:qijianping@fudan.edu.cn

电话:021-51980084

学历:博士

           

教育经历

2004.092009.07 中国药科大学药剂学专业

2000.092004.07 中国药科大学药物制剂专业

 

工作经历

2021.12–至今复旦大学药学院,教授

2015.032016.03 美国加州大学圣芭芭拉分校(UCSB)化学工程系,访问学者

2014.122021.12 复旦大学药学院,副教授

2009.072014.12 复旦大学药学院,讲师 

 

承担科研项目情况

1.主持,国家自然科学基金面上项目(82073801),基于共熔原理的“生物溶剂”促进药物溶解和渗透作用及机制研究,2021.1-2024.12.

2.主持,国家自然科学基金面上项目(81872826),新型“水淬灭”近红外荧光探针的设计及其在纳米粒体内过程研究中的应用,2019.1-2022.12.

3.主持,上海市浦江人才计划(18PJD001),基于跨“穹顶陷阱”促进生物大分子经口服吸收的研究,2018.9.1-2020.8.31

4.主持,上海市自然基金(18ZR1404100),口服pH敏感棒状结构纳米载体靶向炎症性肠病(IBD)的研究,2018.6.1-2021.5.31.

5.主持,上海市自然基金(15ZR1403000),基于荧光共振能量转移效应(FRET)研究脂质体在胃肠道内的转运机制,2015.1-2017.12

6.主持,国家自然科学青年项目(81001405),控制“脂质纳米粒”作为整体单元释放的研究,2011.1-2013.12.

7.主持,上海市科委科技发展基金(1052nm03600),以纳米乳为核的海藻酸纳米囊提高蛋白类药物口服生物利用度的研究,2010.3-2012.6.

8.主持,上海市卫生局青年科研基金,天然酪蛋白纳米胶束作为难溶性药物载体的研究,2013.1-2015.12.

9.企业合作项目

 

研究方向

1.生物大分子药物非注射给药系统的研究

2.新型药用材料的研究

3.口服纳米给药系统的设计及体内转运机制

   

学术兼职

1.Frontiers in Drug Delivery副主编(口服递送)

2.International Journal of Pharmaceutics, Chinese Chemical LettersPharmaceuticals, Current Drug DeliveryChemical Pharmaceutical BulletinBiological Pharmaceutical Bulletin编委

3.Asian Journal of Pharmaceutical Sciences青年编委

4.教育部高等学校药学类专业认证专家

5.中国医药生物技术协会纳米生物技术委员会,委员

6.中国颗粒学会,青年理事

7.中国颗粒学会药物制剂及粒子设计专委会,委员

8.中国实验动物学会屏障医学专委会,常务委员

9.中国整形美容协会形塑与综合技术转化分会,常务理事

 

代表性论著

在药剂学及纳米医学等国际重要学术期刊上发表多篇SCI 论文, 5年来代表性论文如下:

1.Wenjuan Liu, Luyu Zhang, Zirong Dong, Kaiheng Liu, Haisheng H, Yi Lu, Wei Wu, Jianping Qi*. Rod-like mesoporous silica nanoparticles facilitate oral drug delivery via enhanced permeation and retention effect in mucus. Nano Research, 2022, https://doi.org/10.1007/s12274-022-4601-2.

2.Luyu Zhang, Zirong Dong, Wenjuan Liu, Xiying Wu, Haisheng He, Yi Lu, Wei Wu, Jianping Qi*. Novel Pharmaceutical Strategies for Enhancing Skin Penetration of Biomacromolecules. Pharmaceuticals, 2022, 15(7): 877.

3.Xiying Wu, Jingjing Xuan, Qin Yu, Wei Wu, Yi Lu, Quangang Zhu, Zhongjian Chen, Jianping Qi*. Converting Tretinoin into Ionic Liquids for Improving Aqueous Solubility and Permeability across Skin. Pharmaceutical Research, 2022, https://doi.org/10.1007/s11095-022-03238-6.

4.Xiying Wu, Quangang Zhu, Zhongjian Chen, Wei Wu, Yi Lu, Jianping Qi*. Ionic liquids as a useful tool for tailoring active pharmaceutical ingredients. Journal of Controlled Release, 2021, 338: 268-283.

5.Quangang Zhu, Zhongjian Chen, Pijush Kumar Paul, Yi Lu, Wei Wu*, Jianping Qi*. Oral delivery of proteins and peptides: Challenges, status quo and future perspectives. Acta Pharmaceutica Sinica B 2021, 11(8):2416-2448.

6.Zirong Dong, Wenjuan Liu, Kaiheng Liu, Yi Lu, Wei Wu, Jianping Qi*, Zhongjian Chen*. Effects on immunization of the physicochemical parameters of particles as vaccine carriers. Drug Discovery Today 2021, 26(7): 1712-1720.

7.Wenjuan Liu, Zirong Dong, Kaiheng Liu, Yi Lu, Wei Wu, Jianping Qi*, Zhongjian Chen*. Targeting strategies of oral nano-delivery systems for treating inflammatory bowel disease. International Journal of Pharmaceutics 2021, 600: 120461.

8.Xiying Wu, Qin Yu, Jing Wu, Tian Li, Ning Ding, Wei Wu, Yi Lu, Quangang Zhu, Zhongjian Chen, Jianping Qi*. Ionic liquids containing ketoconazole improving topical treatment of T. Interdigitale infection by synergistic action. International Journal of Pharmaceutics 2020, 589: 119842.

9.Wenjuan Liu, Dong Li, Zirong Dong, Kaiheng Liu, Haisheng He, Yi Lu, Wei Wu, Qinghua Li, Li Gan, Jianping Qi*. Insight into the in vivo translocation of oral liposomes by fluorescence resonance energy transfer effect. International Journal of Pharmaceutics 2020, 587: 119682.

10.Xiying Wu, Hongmin Zhang, Shuhua He, Qin Yu, Yi Lu, Wei Wu, Ning Ding, Quangang Zhu, Zhongjian Chen, Yuhua Ma, Jianping Qi*. Improving dermal delivery of hyaluronic acid by ionic liquids for attenuating skin dehydration. International Journal Biological Macromolecules 2020, 150: 528-535.

11.Jinlong Yang, Zhirong Dong, Wenjuan Liu, Haisheng He, Wufa Fan, Yi Lu, Wei Wu, Li Gan*, Jianping Qi*. Discriminating against injectable fat emulsions with similar formulation based on water quenching fluorescent probe. Chinese Chemical Letters 2020, 31: 875-879.

12.Yang Li, Xiying Wu, Quangang Zhu, Zhongjian Chen, Yi Lu, Jianping Qi*, Wei Wu. Improving the hypoglycemic effect of insulin via the nasal administration of deep eutectic solvents. International Journal of Pharmaceutics 2019, 569: 118584.

13.Jianping Qi, Xiongwei Hu, Xiaochun Dong, Yi Lu, Huiping Lu, Weili Zhao, Wei Wu*. Towards more accurate bioimaging of drug nanocarriers: turning aggregation-caused quenching into a useful tool. Advanced Drug Delivery Reviews 2019, 143: 206-225.

14.Xiying Wu, Zhongjian Chen, Yang Li, Qin Yu, Yi Lu, Quangang Zhu, Ying Li, Duopeng An, Jianping Qi*, Wei Wu*. Improving dermal delivery of hydrophilic macromolecules by biocompatible ionic liquid based on choline and malic acid. International Journal of Pharmaceutics 2019, 558:380-387.

15.戚建平,卢懿,董肖椿,赵伟利,吴伟*. 纳米药物载体体内命运研究:环境响应型荧光染料的应用. 药学学报,20195411):1965-1975.

16.Jie Zhuang, Dandan Wang, Dong Li, Yinqian Yang, Yi Lu, Wei Wu, Wei Wu*, Jianping Qi*. The influence of nanoparticles shape on bilateral exocytosis from Caco-2 cells. Chinese Chemical Letters 2018, 29(12): 1815-1818.

17.Dong Li, Jie Zhuang, Yinqian Yang, Dandan Wang, Jinlong Yang, Haisheng He, Wufa Fan, Amrita Banerjee, Yi Lu, Wu Wei, Li Gan*, Jianping Qi*: Loss of Integrity of Doxorubicin Liposomes during Transcellular Transportation Evidenced by Fluorescence Resonance Energy Transfer Effect. Colloids and Surfaces B: Biointerfaces 2018; 171: 224-232.

18.Jianping Qi, Jie Zhuang, Yi Lu, Wei Wu*: Exploiting or overcoming the dome trap for enhanced oral immunization and drug delivery. Journal of Controlled Release 2018; 275: 92-106.

19.Dong Li, Jie Zhuang, Haisheng He, Sifan Jiang, Amrita Banerjee, Yi Lu, Wei Wu, Samir Mitragotri, Li Gan*, Jianping Qi*: Influence of particle geometry on gastrointestinal transit absorption following oral administration. ACS Applied Materials & Interfaces 2017; 9: 42492-42502.

20.Jianping Qi, Jie Zhuang, Yi Lu, Xiaochun Dong, Weili Zhao, Wei Wu*: In vivo fate of lipid-based nanoparticles. Drug discovery today 2017; 22(1): 166-172.